I am particularly interested in deciphering how Staphylococcus aureus regulates its virulence through small RNAs. Small RNAs are an underappreciated mechanism of post-transcriptional regulation that allows for fine control of gene expression. I am focused on the involvement of those sRNAs expressed in vivo and their importance during the pathogenesis process. I use S. aureus clinical isolates from patients as well as in vitro conditions mimicking the infectious site. Overall, I seek to unravel sRNAs expressed in vivo and their role in the pathogenesis process of S. aureus.
I graduated from my bachelor's degree in biology in Tours, France, and I decided to pursue my university course with a master's degree in Infectious Diseases (ICMVAT). I had the opportunity to conduct my first research project on Streptococcus agalactiae during my master's degree and I decided to embark on a PhD program in Lyon, France, at the CIRI International Center for Infectious Disease Research (Centre International de Recherche en Infectiologie).
I was extremely enthusiastic about my research topic, which focused on the interaction between Staphylococcus aureus and Pseudomonas aeruginosa in cystic fibrosis lungs.
After successfully graduating, I continued my research on S. aureus small RNA at Ohio University in Dr. Carroll's lab for 3 years. I then joined the Whiteley lab to futher my reserach on sRNA in S. aureus.
I now live in Newnan, GA, with my extremely talented artist wife, our two daughters, two cats, one gecko (more like a puppy than a gecko), and I've lost track of the number of fish we have. I love photography and astrophotography, cooking, hiking, rubgy and football (the one that is played with feet, aka soccer).
Click here for a list of publications from Paul.